Epidemiological Aspects of Zika Virus Infection Cases among Overseas Travelers in Korea and Japan
1Faculty of Health and Nutrition, Otemae University, Osaka, Japan, 2College of Veterinary Medicine, Konkuk University, 3Magok Sky Internal Medicine, Seoul, KoreaCorrespondence to:
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Korean J Aerosp Environ Med 2022; 32(3): 89-93
Published December 31, 2022
Copyright © Aerospace Medical Association of Korea.
Methods: Raw data of ZIKV infection cases from the Korea Diseases Control and Prevention Agency, and the National Institute of infectious Diseases in Japan, 2016–2020.
Results: There were 33 cases of ZIKV infection in Korea and 21 cases in Japan between 2016 and 2020. Cumulative incidence rate per 1,000,000 overseas travelers (OTs) of Korea (0.30) did not substantially differ that of Japan (0.27), respectively. We observed the ZIKV infected cases of male (69.7% of total cases) were much more than that for female (30.3%) in OTs of Korea (P<0.05). However, while there was none significant differences level between males (52.4%) and females (47.6%) in OTs of Japan. On the other hands, the distribution by adjusted-age groups for ZIKV infections were similar between Korean and Japanese that total cases occurred in the over 20 to 59-years old age, clearly more showing a higher infected of ZIKV (P<0.01). The presumptive origin imported ZIKV infection cases in Korean were as follows; Southeast Asia (81.8% of total cases) and Central & South Americas (18.2%), and those in Japan, these were Southeast Asia (42.9%) and Central & South Americas (42.9%) and Oceania (4.7%), respectively.
Conclusion: This study demonstrates that there is a similar pattern of imported ZIKV disease cases in Korea and Japan. Therefore, to prevent ZIKV infections, greater attention should be paid to individuals who are planning to travel to the presumptive regions of ZIKV.
- World Health Organization (WHO). Zika virus [Internet]. Geneva: WHO; 2018 [updated 2022 Dec 8; cited 2022 Sep 27]. Available from: https://www.who.int/news-room/factsheets/detail/zika-virus.
- Dick GW, Kitchen SF, Haddow AJ. Zika virus. I. Isolations and serological specificity. Trans R Soc Trop Med Hyg 1952;46:509-520. https://doi.org/10.1016/0035-9203(52)90042-4
- Jang HC, Park WB, Kim UJ, Chun JY, Choi SJ, Choe PG, et al. First imported case of Zika virus infection into Korea. J Korean Med Sci 2016;31:1173-1177. https://doi.org/10.3346/jkms.2016.31.7.1173
- Taira M, Ogawa T, Nishijima H. et al. The first case of Zika virus isolated from a Japanese patient who returned to Japan from Fiji in 2016. Jpn J Infect Dis 2017;70:586-589.
- Kutsuna S. Zika virus infection: clinical overview with a summary of Japanese cases. Clin Exp Neuroimmunol 2017;8:192-198. https://doi.org/10.1111/cen3.12408
- Korea Disease Control and Prevention Agency (KDCA). Zika virus disease (2016-2020) [Internet]. Cheongju: KDCA; 2020 [cited 2022 Sep 7]. Available from: https://www.kdca.go.kr/npt/biz/npp/ist/simple/simplePdStatsMain.do?icdCd=NC0026&icdgrpCd=03.
- National Institute of Infectious Diseases (NIID). Zika virus disease (2016-2020). Infectious diseases weekly report [Internet]. Tokyo: NIID; 2020 [cited 2022 Sep 7]. Available from: https://www.niid.go.jp/niid/ja/idwr.html/.
- Korea Tourism Organization. Number of Korean overseas travers (2016-2020). [Internet]. Daejeon: Statistics Korea; 2022 [cited 2022 Sep 8]. Available from: http://www.index.go.kr/potal/main/EachDtlPageDetail.do?idx_cd=1655#quick_02.
- Japan National Tourism Organization. Japanese overseas travelers. [Internet]. Tokyo: Japan Tourism Statistics; 2022 [cited 2022 Sep 8]. Available from: https://statistics.jnto.go.jp/en/graph/#graph--outbound--outgoing--transition.
- Nishiura H, Kinoshita R, Mizumoto K, Yasuda Y, Nah K. Transmission potential of Zika virus infection in the South Pacific. Int J Infect Dis 2016;45:95-97. https://doi.org/10.1016/j.ijid.2016.02.017
- Centers for Disease Control and Prevention (CDC). Travelrelated infectious diseases. [Internet]. Atlanta (GA): CDC; 2022 [cited 2022 Sep 8]. Available from: https://wwwnc.cdc.gov/travel/yellowbook/2020/travel-related-infectiousdiseases/zika.
- Musso D, Ko AI, Baud D. Zika virus infection - after the pandemic. N Engl J Med 2019;381:1444-1457. https://doi.org/10.1056/NEJMra1808246
- Centers for Disease Control and Prevention (CDC). Zika cases in the United States. [Internet]. Atlanta (GA): CDC; 2021 [cited 2022 Sep 8]. Available from: http://www.cdc.gov/zika/reporting/index.html/.