The space environment is a harsh space for humans who have evolved for a long time by adapting to the earth environment. The cosmic conditions that humans experience in outer space including the moon and Mars, such as altered gravity, exposure to cosmic radiation, changes in atmospheric pressure, and lunar dust, not only make the human body uncomfortable but also threaten survival. Space medicine is one of a field of environmental medicine that aims to clarify the physiology and response of body to these harmful space conditions. The primary purpose of space medicine is to protect the health and life of astronauts, and to support mission performance to succeed in space exploration. In addition, it contributes to mankind by utilizing and industrializing the knowledge and technology acquired in the process of developing knowledge about medical countermeasures, basic life support in the space.